Abstract
Background: Lymph node enlargement presents a clinical problem whose significance can range from trivial to critical, depending on the cause of lymphadenopathy. Diseases involving the lymph node fall primarily into three categories, which include lymphadenitis, metastatic malignancies, malignant lymphoma. It is not feasible to excise every enlarge lymph node. So clinical selection of patients must take place and diagnosis of definite causes of lymphadenopathy by histological examination is essential for appropriate treatment. Objective: The aim was to find the relation and association of proportion of different types of lymphadenopathy with age and gender. Materials and method: This cross sectional study was done in Delta Hospital Limited, Dhaka, Bangladesh during the period of May 2010 to December 2010. A total 88 cases were studied irrespective of age, sex along with clinical diagnosis. Results: Among the study subjects 55.7% was being benign lesions and remaining were with malignant lesions. Among the benign lesions majority (31.8%) were tuberculosis with female predominance which commonly occurs below the age of 20 years, where as non-Hodgkins lymphoma (33.3%) was the commoner form among malignant cases with male predominance occurs in older age group. Mean (±) age of benign and malignant cases was 22.1 (±12.73) years and 44.1 (±17.37) years respectively. Conclusion: The present study revealed that lymphadenopathy occurs more commonly in the middle age group with predominance of benign lesions. Among the benign lesions tuberculosis is the most common one and non-Hodgkins lymphoma is the commonest malignant lesion.DOI: http://dx.doi.org/10.3329/dmcj.v1i1.14969 Delta Med Col J. Jan 2013;1(1):8-12
Highlights
Lymph nodes are one of the components of the lymphoreticular system, which includes the thymus, spleen and tonsils as well as organized lymphoid tissue in the bone marrow and mucosa associated lymphoid tissue (MALT).[1]
The study was aimed at assessing the relation between histological subtypes of lymphadenopathy with two major demographic variables age and sex
Reactive hyperplasia was the predominant lesion (51%) in a study done by Moore et al.[14] followed by lymphoma (19%), metastatic carcinoma (15%) and tubercular lymphadenitis (15%)
Summary
Lymph nodes are one of the components of the lymphoreticular system, which includes the thymus, spleen and tonsils as well as organized lymphoid tissue in the bone marrow and mucosa associated lymphoid tissue (MALT).[1]. Not all patients with palpable lymph nodes require biopsy, and the finding of benign disease requiring no further treatment is common.[2]. Lymphadenopathy is caused by the invasion or propagation of either inflammatory cells or neoplastic cells into the node. It results from a vast array of disease processes.[3]. Among the benign lesions majority (31.8%) were tuberculosis with female predominance which commonly occurs below the age of 20 years, where as non-Hodgkin’s lymphoma (33.3%) was the commoner form among malignant cases with male predominance occurs in older age group. Conclusion: The present study revealed that lymphadenopathy occurs more commonly in the middle age group with predominance of benign lesions. Among the benign lesions tuberculosis is the most common one and non-Hodgkin’s lymphoma is the commonest malignant lesion
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
