Abstract
SummarySkin graft experiments with pig siblings from semi‐inbred and outbred families confirmed the existence of a pig main histocompatibility system (MHS). Grafts exchanged between serological (lymphocytotoxicity) MHS incompatible siblings from outbred matings survived 5.6 days and between compatible animals 9.8 days. In compatible pairs from semi‐inbred matings they survived 22.4 days and in incompatible individuals 6.1 days. Skin grafts exchanged between individuals with E blood group compatibility led to the formation of haemagglutinating and lym‐phocytotoxic antibodies reacting with some E antigens. The results indicate that the survival of skin grafts in semi‐inbred pigs is apparently influenced also by differences in the E system.
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