Abstract
Summary o 1.Glycogen and ribonucleic acid have been studied histochemically in serial biopsies of human skin autografts and homografts. 2.During the latent phase before homograft destruction the epithelium of homografts and autografts shows similar changes in glycogen and ribonucleic acid content. 3.There is no major change in glycogen content of homograft epidermis prior to destruction. 4.The homogeneous polysaccharide-containing component of the basement membrane between epidermis and dermis appears unchanged at the time of destruction of the epidermis. 5.The possible role of ribonucleoprotein in the mechanism of homograft destruction is discussed.
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