Abstract
A histochemical investigation of one hundred placentas was carried out. Twenty of these placentas were from patients with severe toxemia and pre-eclampsia and 10 from patients with intrauterine fetal death. Seventy placentas contained one or more infarcts in different stages of progress.The placentas were incubated in substrates to demonstrate the activity of the following enzymes: alkaline and acid phosphatase, 5-nucleotidase, and adenosinetriphosphatase, leucine aminopeptidase, succinate dehydrogenase, lactate dehydrogenase, β-hydroxybutyrate dehydrogenase, isocitrate dehydrogenase, and glucose-6-phosphate dehydrogenase.Evidence is presented to support the theory of a disturbance of the maternal rather than the fetal circulation as a cause of placental infarction.
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