Abstract

Germ cell tumors (GCTs) are unique in their ability to differentiate along multiple cell lineages. The strong association between primary mediastinal non-seminomatous germ cell tumors and hematologic malignancies is well known. The most common hematologic neoplasms seen with GCTs are acute megakaryoblastic leukemia and histiocytic sarcoma. GCT patients with hematologic malignancies have a much worse prognosis than patients …

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