Abstract
THE presence of biogenic amines has been reported in a number of plants1,2. Although they are found most widely distributed in fungi, their presence in higher plants has been made more evident by work in recent years, and a survey of the physiologically active amines in fruits and vegetables by Udenfriend et al.3 revealed a wide variety of these compounds. Holtz4 had shown earlier that extracts of tomato and spinach had a physiological action in animals similar to histamine, and Werle and Raub5 extended this work to a survey of many plant genera. In this survey, water extracts of Trifolium pratense and Trifolium repens were shown to have slight histamine-like activity. The presence of histamine, N-dimethyl histamine, N-acetyl histamine and acetylcholine in Spinacea oleracea has since been confirmed by Appel and Werle6. Colamine has been shown to be present in grass14 and the presence of other amines is also suggested.
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