Abstract
Although our experience with hyposensitization, extending over a period of eighteen years, has taught us conservatism, we find that we can safely conclude that: 1. 1. Typhoid split-protein and histamine are both useful in the treatment of allergic cases, be they skin, respiratory, bacterial, or digestive. 2. 2. Typhoid split-protein is much safer than histamine, although not quite so rapid nor so powerful in its effect. 3. 3. Small intradermal doses of either will work better and more safely than large doses. 4. 4. Histamine injections may precipitate acute asthma; this, however, can be easily controlled with adrenalin. 5. 5. Histamine in the aged or arteriosclerotic, if used at all, should be employed carefully in minute doses.
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