Abstract

A review of forty patients with Hirschsprung's disease who were treated at the University of Michigan Medical Center from 1950 to 1963 is presented and the findings studied in relation to other series reported in the literature. The clinical features analyzed included extent of aganglionosis, age of patient when first seen in the hospital, sex distribution, chief complaints, associated anomalies and complications. The importance of early diagnosis and appropriate surgical treatment of this distressing disease in infancy is stressed. The morbidity and mortality encountered in simple colostomy and Swenson's operation are reported in detail. An analysis of the seven deaths in our series shows that peritonitis was present in all but that enterocolitis and residual aganglionosis were the primary causes of the fatal outcome.

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