Abstract

The present study was conducted to compare the effects on several immobility reactions of hippocampal ablation in rats. Hippocampal lesions were found to increase significantly the duration of restraint-induced immobility, but these same lesions significantly increased movement in response to footshock and in an open field, indicating a reduction in the tendency for rats with hippocampal lesions to become immobile in these situations. These results are interpreted as indicating that hippocampal lesions in animals do not inevitably lead to a decreased tendency to become immobile in stressful situations and that the hippocampus in the adult rat inhibits behaviors which immature rats demonstrate more readily than mature rats.

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