Abstract
The effects of gross hippocampal aspiration were compared with those of frontal cortical lesions on wheel running and generalized activity of rats during control and arousal conditions. The rate of recovery of these functions was then measured in animals with hippocampal lesions or with combined hippocampal and frontal lesions. From these studies, it appears that the hippocampus shares arousal control functions with frontal cortex, that it is partially responsible for the recovery that has been reported to occur after frontal lesions, but does not itself recover after damage.
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