Abstract
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia appears in the WHO classification of thoracic tumours since 1999 as a preinvasive epithelial lesion characterized by a proliferation of scattered and isolated cells, small nodules (neuroendocrine bodies) or linear pulmonary neuroendocrine cell proliferations, confined to the bronchial or bronchiolar epithelium, including extraluminal local proliferations (tumorlets or carcinoids). In this review we update the recently established quantitative morphological criteria and new qualitative aspects are considered to contribute to a better characterization of the entity.
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