Abstract

A new clinical sign in sarcoglycanopathies is described. Patients with sarcoglycanopathies showed a phase of abduction of the thighs while rising from the ground: the hip abduction sign. The sign results from selective weakness of hip adductors and comparative preservation of hip abductors. This sign had a sensitivity of 76.2%, specificity of 98%, and was most conspicuous between 3 and 10 years of disease duration. The hip abduction sign is an important clinical indicator of sarcoglycanopathies.

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