Abstract

High-level spinal cord injuries often result in paralysis of all four limbs, leading to decreased patient independence and quality of life. Coordinated functional electrical stimulation (FES) of paralyzed muscles can be used to restore some motor function in the upper extremity. To coordinate functional movements, FES controllers should be developed to exploit the complex characteristics of human movement and produce the intended movement kinematics and/or kinetics. Here, we demonstrate the ability of a controller trained using reinforcement learning to generate desired movements of a horizontal planar musculoskeletal model of the human arm with 2 degrees of freedom and 6 actuators.The controller is given information about the kinematics of the arm, but not the internal state of the actuators.In particular,we demonstrate that a technique called “hindsight experience replay” can improve controller performance while also decreasing controller training time.

Highlights

  • P EOPLE with high-level (C1-C4) spinal cord injuries (SCIs) often develop paralysis of all four limbs - a condition known as tetraplegia

  • Controllers that were able to acquire some targets frequently moved indirectly towards the target and acquired the target near the edge of the target region (Figure 5b). We provided these controllers with additional training time, and the controllers were able to learn to acquire nearly 100% of targets, suggesting that this behavior can be resolved by providing additional training time, or by retraining

  • Providing additional training time to controllers that did not produce movement did not improve results, suggesting that these controllers found local maximums in the reward function by minimizing muscle activity without acquiring any targets. These results suggest a mechanism for the success of hindsight experience replay (HER)-based algorithms in controlling Functional electrical stimulation (FES)-actuated MIMO human arms

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Summary

Introduction

P EOPLE with high-level (C1-C4) spinal cord injuries (SCIs) often develop paralysis of all four limbs - a condition known as tetraplegia. Functional electrical stimulation (FES) can be used to activate some paralyzed muscles and restore motor function to people with paralysis. When combined with an appropriate controller to coordinate the muscle contractions over time, as well as a command source that people can use to convey their intended movements, FES can produce functional movements [1], [2]. The movements produced by FES can greatly increase independence and quality of life for people with paralysis [1]. Manuscript received November 5, 2020; revised February 15, 2021 and April 19, 2021; accepted April 21, 2021. Date of publication May 17, 2021; date of current version June 8, 2021.

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