Hilbert Transform and Statistical Analysis for Channel Selection and Epileptic Seizure Prediction

Abstract

This paper is concerned with Electroencephalography (EEG) seizure prediction, which means the detection of the pre-ictal state prior to ictal activity occurrence. The basic idea of the proposed approach for EEG seizure prediction is to work on the signals in the Hilbert domain. The operation in the Hilbert domain guarantees working on the low-pass spectra of EEG signal segments to avoid artifacts. Signal attributes in the Hilbert domain including amplitude, derivative, local mean, local variance, and median are analyzed statistically to perform the channel selection and seizure prediction tasks. Pre-defined prediction and false-alarm probabilities are set to select the channels, the attributes, and bins of probability density functions (PDFs) that can be useful for seizure prediction. Due to the multi-channel nature of this process, there is a need for a majority voting strategy to take a decision for each signal segment. Simulation results reveal an average prediction rate of 96.46%, an average false-alarm rate of 0.028077/h and an average prediction time of 60.1595 min for a 90-min prediction horizon.