High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

Antonia Beteva ,S Delageniere,S Monaco,X Thibault,L Launer,F Cipriani,J Mccarthy,Sine Larsen ,Pétra Pernot ,R.g.b Ravelli ,Pascal Théveneau ,Jens Meyer ,Didier Nurizzo ,William Shepard ,Olof Svensson ,Romeu André Pieritz ,David R Hall ,Stephen Cusack ,Edward P Mitchell ,C.b Lavault ,Darren Spruce ,E Gordón ,Vicente Rey ,Martin A Walsh ,A.a Mccarthy ,J.p Turkenburg ,David I Stuart ,Trevor Mairs ,Gordon A Leonard ,José Gabadinho ,Matias Guijarro ,Seán Mcsweeney

doi:10.1107/s0907444906032859

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

Antonia Beteva , S Delageniere + Show 30 more

Open Access

https://doi.org/10.1107/s0907444906032859

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Journal: Acta Crystallographica Section D Biological Crystallography	Publication Date: Sep 19, 2006
Citations: 64	License type: CC BY 2.0 UK

Affiliation: European Science Foundation, European Molecular Biology Laboratory, University of York, Wellcome Centre for Human Genetics

#Structural Proteomics In Europe #Automatic Data-collection System + Show 8 more

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Abstract

An automatic data-collection system has been implemented and installed on seven insertion-device beamlines and a bending-magnet beamline at the ESRF (European Synchrotron Radiation Facility) as part of the SPINE (Structural Proteomics In Europe) development of an automated structure-determination pipeline. The system allows remote interaction with beamline-control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.

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