High-Sensitive Sensor of Dopamine Based on Photoluminescence Quenching of Hierarchical CdS Spherical Aggregates

Binjie Sun,Changzheng Wang

doi:10.1155/2012/502481

Abstract

Hierarchical CdS spherical aggregates have been fabricated by an assembling strategy starting from nanoparticles, which opens a general way to obtain hierarchical spherical aggregates of different types of materials. The hierarchical CdS spherical aggregates are of high porosity and high surface area, which give rise to unique photoluminescence properties. The desirable properties we report here will spur further developments of novel dopamine photoluminescence sensors based on the high surface area hierarchical CdS spherical aggregates fabricated with our unique assembling strategy. The novel dopamine photoluminescence sensor has a low detection limit of1.0×10−8 M, which is much lower than those reported previously.

Highlights

Dopamine (DA), as one of the most important neurotransmitters, was discovered in the 1950s, which has ever since captured the interest of neuroscientists and chemists
Fluorescence quenching refers to any process which decreases the fluorescence intensity of a sample, which has been widely studied both as a fundamental phenomenon and as a source of information about biochemical systems [8,9,10]
scanning electron microscope (SEM) images testify the formation of hierarchical CdS spherical aggregates

Summary

Introduction

Dopamine (DA), as one of the most important neurotransmitters, was discovered in the 1950s, which has ever since captured the interest of neuroscientists and chemists. The detection of DA is most often accomplished by the measurement of redox potential or intrinsic fluorescence. With the development of nanotechnology, many methods have been developed to detect DA by using nanomaterials such as carbon nanotubes and gold nanoparticles (NPs) [11,12,13,14,15]. Semiconductor nanoparticles have attracted much attentions since they have unique optical and several other properties such as size-dependent, tunable adsorption and emission properties [16]. Fluorescence detection methods have led to major improvement in bioanalytical applications because of their extraordinary sensitivity and selectivity. The traditional fluorescence probes are organic dyes, and semiconductor nanocrystals with unique structure could probably be used to substitute the organic dyes based on their unique optical properties

Methods

Results

Conclusion