HIGH-RISK HYPERTENSIVE PATIENTS: ASSESSMENT OF BLOOD PRESSURE CONTROL, ADHERENCE TO FIXED-DOSE COMBINATION TREATMENTS AND SATISFACTION: PP.5.201

Abstract

Objectives: To evaluate the blood pressure (BP) control, adherence to medication and satisfaction of high or very high-risk hypertensive patients undergoing fixed-dose combination treatment. Design and Method: Epidemiological, cross-sectional, multicentre study. General practitioners (n= 391) recruited high or very high-risk patients who had been diagnosed of hypertension at least one year before. Sociodemographic (working status, cohabitation, level of education), and clinical data (age, sex, BMI, familiar history, BP measurement, blood tests, cardiovascular disease, diabetes, and prescriptions) were collected. BP control was measured by means of both the clinicians' impression and observing the limit under 140/90 mmg/Hg (or 130/80 mmg/Hg if diabetes, cardiovascular or chronic renal disease). Patients's compliance and satisfaction were measured by using the Morisky-Green Test, and the SAT-Q questionnaire, respectively. Chi2 test and odd's ratio were calculated to analyze the association between BP control, adherence, patients' risk and sex. Student's test was applied to test differences in satisfaction according to BP control and adherence. Logit models were calculated to predict BP control by using patient' clinical data, compliance and satisfaction. Results: In total 1517 patients (46.87% female) were sampled (mean age = 66.1). Very high risk was detected in 63% of patients (more often amongst males). Only 16.41% had BP controlled. At contrast, clinicians considered 68.9% of them with BP controlled. Moreover, a low percentage of adherence (28.70%) was found. BP control and adherence was associated (Chi2 = 12.48; p< 0.001; OR = 1.68; IC 95%: 1.258 – 2.254). Significant differences in satisfaction were found according to BP control and compliance (59.56 vs 65.99; p< 0.001 and 67.59 vs 57.37; p< 0.001; respectively). Finally, clinical and sociodemographic data explained a low proportion of BP control (R2= 0.15). Conclusions: A low rate of BP control and adherence was found between high or very high risk patients undergoing antihypertensive regimens. Although BP control, patients' adherence, and satisfaction seem to be associated, further investigations are needed to improve BP control.