High‐resolution spectral domain optical coherence tomography findings in reticular pattern dystrohy

Abstract

AbstractPurpose To analyze specific outer retinal and retinal pigment epithelium (RPE) features in reticular pattern dystrophy using spectral‐domain optical coherence tomography (SD‐OCT).Methods Consecutive patients with reticular pattern dystrophy underwent a complete ophthalmologic examination, including assessment of best‐corrected visual acuity (BCVA), fundus biomicroscopy, and SD‐OCT (Spectralis SD‐OCT, Heidelberg Engineering). Outer retinal and RPE macular features, as evaluated by SD‐OCT (scan passing through the fovea) were analyzed by 3 authors (JZ, NM and GQ).Results 24 eyes of 13 patients (5 males, 8 women, mean age 71.4) were included. Mean visual acuity was measured at 0.30 (logMAR). The RPE layer in the foveal area appeared normal in 41.7% of scans, while small RPE elevations and RPE bumps were detected in 33.3% and 20.8% of scans, respectively. Inner segment/outer segment (IS/OS) junction appeared disrupted in 50% of scans, and absent in 58.3% of scans. SD‐OCT showed a slight IS/OS elevation in 54.2% of scans. The external limiting membrane (ELM), appeared disrupted in 50% of scans, absent in 37.5% of scans, and elevated in 66.7% of scans. Hypereflective subretinal material accumulation or hyporeflective subretinal lesions, were detected in 33.3% and in 12.5% of scans, respectively. SD‐OCT showed hyporeflective retinal pseudocysts in 16.7% of scans.Conclusion In this series of reticular pattern dystrophy, SD‐OCT showed disruption of RPE layer and RPE bumps. Outer retinal changes included absence and disruption of both IS/OS junction and ELM. Hypereflective subretinal material accumulation or hyporeflective subretinal lesions, and hyporeflective retinal pseudocysts were also noticed.