Abstract

Introduction: Moebius syndrome typically presents as congenital facial palsy with abduction impairment. We used MRI to examine a family with features of Moebius syndrome. Methods: We examined three related family members with complete opthalmoplegia, blepharoptosis, and facial diplegia. Orbits were imaged with T1-weighting in quasi-coronal and sagittal planes using surface coils. Intraorbital resolution was 234 to 312 microns within 1.5- to 2.0-mm-thick planes. Cranial nerves (CNs) were imaged at the brainstem using head coils and T2-weighting, yielding resolution of 195 microns in planes 1.0 mm thick.

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