Abstract

Abstract A “signal-on” electrochemical sensing strategy was designed for highly sensitive and selective detection of mercury (II) via its induction to three-way junction of DNA (DNA-TWJ). The TWJ consisted of the capture probe that was self-assembled on a gold electrode surface through S Au bond, the signal probe that was labeled with ferrocene (Fc) and contained single T–T mismatch to capture probe, and an assistant probe for the formation of DNA-TWJ upon the presence of mercury (II). This process caused the Fc tag approaching the electrode for fast electron transfer and thus increased the oxidation current. The “signal-on” sensing method could detect Hg 2 + ranging from 0.005 to 100 nM. The assay was simple and fast. It showed potential application in on-site and real-time Hg 2 + detection.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.