Highly regio-, diastereo-, and enantioselective Pd-catalyzed allylic alkylation of acyclic ketone enolates with monosubstituted allyl substrates

Abstract

Pd-catalyzed asymmetric allylic alkylation reactions of acyclic ketones with monosubstituted allyl substrates using 1,1'-P,N-ferrocene with H as substituent on the oxazoline ring as ligand gave products having two chiral centers with high yields and with