Abstract
1,4-Dihydropyridines have been recognized as a potential source of hydrogen when undergoing dehydroaromatization. Such strategy has been exploited here for highly enantioselective hydrogenation of quinolines. Reduction proceeds smoothly under mild conditions and minimal investment of the catalyst to give a variety of amine products. The reaction is sensitive to the electron-withdrawing substituents in the 6-position which cause decreased reactivity.
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