Abstract
The catalytic enantioselective Friedel-Crafts reaction of indoles with 2-enoylpyridine 1-oxides has been studied in the presence of chiral pyridine 2,6-bis(5',5'-diphenyloxazoline)-Cu(II) complexes. The reaction furnished alkylated indoles in excellent yields (up to 97%) and enantioselectivities (up to 99% ee).
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