Highly Enantioselective Aryl Additions of [AlAr3(thf)] to Ketones Catalyzed by a Titanium(IV) Catalyst of (S)‐Binol

Abstract

Chiral transfer: Novel asymmetric aryl transfers from [AlAr3(thf)] to a wide variety of ketones are catalyzed by an in situ generated titanium species with (S)-binol as the chiral ligand. The reaction affords tertiary alcohols with enantioselectivities up to 97 % ee (see scheme). Binol=2,2′-dihydroxy-1,1′-binaphthyl. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z701201_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.