Highly Enantiomeric Purity Conversion of α-Sulfinyl Oximes and α-sulfinyl Hydrazones to the Corresponding β-keto Sulfoxides with Butyltriphenylphosphonium Periodate (BUTPPPI)

Abstract

Butyltriphenylphosphonium periodate (Ph3P+BuIO4 −) 1 is readily prepared as a white solid from butyltriphenylphosphonium chloride, performs conversion of α-sulfinyl oximes (2) and α-sulfinyl hydrazones (4) to the corresponding β-keto sulfoxides (3) in high yields and high enantiomeric purity.