Abstract
We demonstrate for the first time the high efficacy of tetranuclear ZnII2LnIII2 coordination clusters (CCs) as catalysts for the Friedel–Crafts (FC) alkylation of indoles with a range of trans-β-nitrostyrenes. The reaction proceeds in good to excellent yields (76%–99%) at room temperature with catalyst loadings as low as 1.0 mol %.
Highlights
For the first time, a highly efficient, tetranuclear 3d/4f catalytic system for the FC alkylation of indoles with nitroalkenes
Products are obtained with a yield of up to 98% at room temperature and with only 1% catalyst loading, showcasing the efficacy of these catalytic species
All chemicals and solvents were purchased from Sigma Aldrich, S.D
Summary
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