Abstract
Abstract The introduction of phenoxy groups at the hydroxy function of N-arylsulfonyl derivatives of trans-4-hydroxy- l -proline resulted in efficient hydrophobic organocatalysts, which could efficiently catalyze the direct aldol reactions of cyclic ketones with a series of aromatic aldehydes in water with excellent yields (99%), anti diastereoselectivities (up to 99%) and enantiomeric excess (99%).
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