Abstract
IVF requires ongoing evaluation and adjustment of modifiable factors in order to continue to improve live birth rates (LBRs). Two cycle characteristics that are potentially modifiable include total gonadotropin (GN) dose and length of controlled ovarian stimulation (COH). Data from autologous fresh IVF-embryo transfer (IVF-ET) cycles indicates that longer COH and higher total GN dose are associated with decreased LBRs1,2. It has been shown that prolonged COH and high GN dose may negatively affect embryo-endometrial synchrony as well as impact oocyte and embryo quality3,4.
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