Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers

Tai-Chung Tseng,Chen-Hua Liu,Ding-Shinn Chen,Chi-Ling Chen,Jia-Horng Kao,Femke Carolien Verbree,Chun-Jen Liu,Wan-Ting Yang,Tung-Hung Su,Cheng-Shiue Tsai,Pei-Jer Chen,Hung-Chih Yang,Chia-Chi Wang,Stephanie Fang-Tzu Kuo

doi:10.1136/gutjnl-2014-306977

Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers

Tai-Chung Tseng, Chen-Hua Liu + Show 12 more

https://doi.org/10.1136/gutjnl-2014-306977

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Journal: Gut	Publication Date: Apr 24, 2014
Citations: 104

Affiliation: Tzu Chi University, Taipei Tzu Chi Hospital, National Taiwan University, National Taiwan University Hospital, Genomics Research Center, Academia Sinica, Medisch Centrum Haaglanden, St Vincent's Hospital

#Basal Core Promoter Mutant #Risk Of Cirrhosis + Show 8 more

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Abstract

Background and objectivePrecore (PC) variant (G1896A) and basal core promoter (BCP) variant (A1762T/G1764A) of HBV are associated with risk of hepatocellular carcinoma in HBV carriers. However, little is known about...

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