Abstract
Within the last 20 years, the opportunities for manufacturing at the nano-level have risen substantially. Despite this growth, the industry continues to face the challenge of obtaining a significant experimental yield that is worthy of the cost to produce at the atomic level. Today, most researchers utilise response surface methodology to evaluate and improve existing techniques in nanoparticle production. While these methods are appropriate for identifying optimal factor settings in the traditional manufacturing process, they require some refinement under significantly elevated degrees of quality. This paper investigates the use of higher-order response surface designs in the improvement of nanomanufacturing processes.
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