Abstract
Epithelial sheets made of cultured oral mucosal epithelial cells have been used to treat various epithelial defects [1]. These epithelial sheets are derived from oral epithelial stem cells exhibiting high proliferation potential. In the skin, research into the keratinocyte stem cell niche has advanced remarkably. However, the oral mucosal stem cell niche is less well understood. Thus, we investigated the density of label-retaining cells (LRC) in different areas of oral mucosa to elucidate the localization of oral mucosal stem cells.
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