Abstract
Kawasaki Disease (KD) is an acute systemic vasculitis of unknown etiology in infants and young children, and it is frequently associated with coronary artery aneurysms. High-dose infusion of IgG (IVIG) effectively reduces systemic inflammation and the incidence of coronary artery lesions in 80-90% of KD. However, for reasons that remain unclear, some patients do not respond to IVIG. In order to obtain clues to the cause of IVIG resistance, we compared the in vitro effects of high-dose IgG on cultured human coronary artery endothelial cells (HCAECs) exposed to various inflammatory stimuli.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
