Abstract

The maintenance of an appropriate intracellular environment is a constant challenge for all living organisms, from prokaryotes to multicellular eukaryotes. Intracellular homeostasis is maintained by transporting various compounds such as ions, sugars, amino acids, and drugs across the cell membrane. Therefore, the analysis of transmembrane transport is crucial to understanding cell physiology as well as for exploring the bioavailability of drugs. In this study, we developed a novel micro-device in which a large number of droplet interface bilayers (> 500) are formed at a time by using femtoliter-sized droplet arrays immobilized on a hydrophobic/hydrophilic substrate.

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