High Surface Area 3D Hierarchical Ni(OH)2-Coated Ni Microflowers for Non-Enzymatic Glucose Sensor with High Sensitivity and Low Detection Limit

Abstract

Glucose detection has attracted considerable interest in diagnosis and management of diabetes mellitus as well as monitoring and controlling the food processing. However, the development of sensitive and accurate glucose sensors with an ultralow detection limit is imperative to prevent type- II diabetes. In this work, the enzyme-free glucose sensor based on high surface area three dimensional (3D) hierarchical Ni microflowers with a Ni(OH)2 coating layer has been demonstrated in a simply single step by a simple single chemical reaction at a low temperature of 80 oC. In addition, our devices exhibit an outstanding detection limit as low as 2.4 nM with a high sensitivity of 2392 µA mM−1cm−2 compared to all Ni based modified electrodes, which is attributed to not only the increased surface area due to the controlled formation of spikes but also the contribution of Ni(OH)2 coating layer.