High-sugar diet affects immunity and metabolism by affecting gut microbiota

Abstract

Due to the rise of global material levels and people's lack of awareness of scientific diets, high-sugar diets are gradually becoming one of the largest diet types in modern humans; some researchers believe that this diet will have negative impact on people’s intestinal flora. The number of bacteria in the human body is known to be extremely large, and the intestinal flora is one of the main components. Their number roughly between 10 and 100 times as many as cells of humans. Owing to several studies, an imbalance in gut microbiota is linked to a variety of information that will support disorders. The present investigation examines the appropriate information on obesity, diabetes, and other disorders, and discusses the potential linkages among these diseases and a high-sugar diet and intestinal flora, in order to figure out if a high-sugar diet might have an unhealthy effect on human immunity and metabolism through gut microbiota. A high-sugar diet can cause excessive proliferation of intestinal Firmicutes and Proteus, disrupting intestinal flora balance, and the root causes of diabetes, weight gain, inflammation of the intestines, and non-alcoholic hepatitis, as well as the corresponding therapeutic mechanisms, are all associated to the excessive growth of certain species of bacteria in the intestines, which also means gut microbiota imbalance.