Abstract
Polyvinyl alcohol (PVA) hydrogels have been proposed for use as promising biomaterials in biomedical and tissue engineering but their poor mechanical and water-retention properties have hindered their development. Graphene oxide (GO), an excellent nanofiller, was added to PVA to make GO/PVA composite hydrogels by a freeze/thaw method. The mechanical properties of the GO/PVA hydrogels were significantly improved. Compared to pure PVA hydrogels, a 132% increase in tensile strength and a 36% improvement of compressive strength were achieved with the addition of 0.8 wt% of GO, which suggests an excellent load transfer between the GO and the PVA matrix. The incorporation of certain amount of GO into composite hydrogels does not affect the toxicity of PVA to osteoblast cells.
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