Abstract
Background: HBV, HCV, HIV and Syphilis are leading transfusion transmitted infections. Blood donors are screened against these infectious diseases before transfusion to patients.Methods: Data of general population and volunteer prisoner blood donors is retrieved from records of January 2007 to September 2009. Data is analysed using Epi Info version 3.5.1. Blood donors were screened using ELISA method against HCV, HBV, and HIV while VDRL method is used for screening against Syphilis.Results: Prevalence of HBV, HCV, HIV, and Syphilis in general population blood donors is 3.3%, 4.7%, 0.51% and 0.47% respectively. Prevalence of HBV, HCV, HIV, and Syphilis in prisoner blood donation is 7.81%. 15.42%, 1.17%, and 7.63% respectively.Conclusion: Prevalence of HBV, HCV, HIV and Syphilis is high in prisoners as compared to general population.
Highlights
Blood and blood products play a vital role for saving lives during surgical procedures and trauma care
Being a prisoner blood donor was associated with higher seropositivity for Syphilis (OR=19.68; CI=12.2-31.99, p = .00), AntiHIV (OR=5.53; CI=2.69-11.46, p = .00), Anti-Hepatitis C virus (HCV) (OR=3.11; CI=2.6-3.73, p = .00) and HBs Ag (OR=2.00; CI=1.62-2.63, p = .00)
FDA has recommended “Current inmates of correctional institutions and individuals who have been incarcerated for more than 72 consecutive hours during the previous 12 months be deferred as donors of Whole Blood, blood components, Source Leukocytes, and Source Plasma for 12 months from the last date of incarceration” FDA considers approval of blood collection from high risk donors for in-vitro, or other special uses, when there are no alternative sources.[FDA] So studies regarding prevalence of these infections among prisoner blood donors are scarce
Summary
Blood and blood products play a vital role for saving lives during surgical procedures and trauma care. In the Punjab, Shaukat Khanum Cancer Hospital, Lahore recorded prevalence of these infections among volunteer and replacement blood donors as HBV 1.46 – 2.99%, HCV 3.01 – 4.99%, HIV 0 - 0.06% and syphilis 0.19 – 0.57% after reviewing ten years blood donation data [11]. The pre-transfusion screening of donated blood for test for HIV, HBV, HCV and Syphilis is vital to ensure the delivery of safe blood to the public [20] Those NGOs in the Punjab, that organize blood donation camps in the Prisons, as well as those arrange in general population, carry out screening of donated blood. The study was conducted to assess the prevalence of HIV, HBV, HCV and syphilis among prisoner blood donors and compare it with general population donors in the Punjab, Pakistan. Conclusion: Prevalence of HBV, HCV, HIV and Syphilis is high in prisoners as compared to general population
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