High Resolution SNP Microarray Analysis is Useful for Diagnosis and Prognosis of Renal Epithelial Neoplasms

Abstract

Renal epithelial neoplasms (REN) are common in adults with approximately 54,000 newly diagnosed cases each year and over 13,000 deaths. Diagnosis and classification of REN can be difficult based upon histologic and clinical information, however, the prediction of which patients will have recurrent disease and/or disease progression is even more challenging. Single nucleotide polymorphism (SNP) microarray analysis has been shown to be useful in stratifying the four major classes of REN for diagnosis into clear cell renal cell carcinoma (RCC), papillary RCC, chromophobe RCC and oncocytoma.