Abstract

Several devices and measurement approaches have recently been developed to perform ballistocardiogram (BCG) and seismocardiogram (SCG) measurements. The development of a wireless acquisition system (hardware and software), incorporating a novel high-resolution micro-electro-mechanical system (MEMS) accelerometer for SCG and BCG signals acquisition and data treatment is presented in this paper. A small accelerometer, with a sensitivity of up to 0.164 µs/µg and a noise density below 6.5 µg/ is presented and used in a wireless acquisition system for BCG and SCG measurement applications. The wireless acquisition system also incorporates electrocardiogram (ECG) signals acquisition, and the developed software enables the real-time acquisition and visualization of SCG and ECG signals (sensor positioned on chest). It then calculates metrics related to cardiac performance as well as the correlation of data from previously performed sessions with echocardiogram (ECHO) parameters. A preliminarily clinical study of over 22 subjects (including healthy subjects and cardiovascular patients) was performed to test the capability of the developed system. Data correlation between this measurement system and echocardiogram exams is also performed. The high resolution of the MEMS accelerometer used provides a better signal for SCG wave recognition, enabling a more consistent study of the diagnostic capability of this technique in clinical analysis.

Highlights

  • Each year, cardiovascular diseases (CVD) cause 3.9 million deaths in Europe, which account for45% of all deaths

  • One of the groups are healthy subjects and the remaining ones were divided by the following pathologies: Dilated cardiomyopathy (DCM), myocardial infarction (MI), aortic stenosis (AS) and hypertrophic cardiomyopathy (HCM)

  • At the beginning of the exam, each participant consented to the exam procedures through an approved informed consent form and their personal information was kept in anonymity

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Summary

Introduction

Cardiovascular diseases (CVD) cause 3.9 million deaths in Europe, which account for. This gives roughly a 5-bit resolution for the full acquisition system which strongly compromises the signal analysis These conditions increase the opportunity of implementing an acquisition system for SCG (and BCG) signals that incorporates a MEMS accelerometer based on pull-in time measurement, extending its application to a more consistent study of the diagnostic capability of this technique. The full SCG analysis system that includes an ECG synchronized signal acquisition, calculates several SCG parameters (based on the measured signals) that are compared to parameters and indexes calculated through an echocardiogram system performed at similar conditions as ECG and SCG acquisition This procedure leads to an improvement (due to the much better signal-to-noise ratio and system resolution) on the SCG peaks recognition and a more consistent study of SCG technique and its diagnostic capability

SCG and ECG Acquisition Device
The Analysis System
SCG Acquisition System Characterization
Sensitivity Characterization
SCG Acquisition System Performance over a Preliminary Clinical Study
Subjects Selection
Measurement Methodology
Session
ECG Analysis
SCG Analysis
ECG and SCG Analysis
Data Comparison and Correlations from Measurement Systems
12. Heartrate
Conclusions and Future Work
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