High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals

Abstract

We report the development of a high spatial resolution tweezers-type coincidence gamma-ray camera for medical imaging.This application consists of large-area monolithic Multi-Pixel Photon Counters (MPPCs) and submillimeter pixelized scintillator matrices.The MPPC array has 4 × 4 channels with a three-side buttable, very compact package.For typical operational gain of 7.5 × 105 at + 20 °C, gain fluctuation over the entire MPPC device is only ± 5.6%, and dark count rates (as measured at the 1 p.e. level) amount to ⩽ 400 kcps per channel.We selected Ce-doped (Lu,Y)2(SiO4)O (Ce:LYSO) and a brand-new scintillator, Ce-doped Gd3Al2Ga3O12 (Ce:GAGG) due to their high light yield and density.To improve the spatial resolution, these scintillators were fabricated into 15 × 15 matrices of 0.5 × 0.5 mm2 pixels.The Ce:LYSO and Ce:GAGG scintillator matrices were assembled into phosphor sandwich (phoswich) detectors, and then coupled to the MPPC array along with an acrylic light guide measuring 1 mm thick, and with summing operational amplifiers that compile the signalsinto four position-encoded analog outputs being used for signal readout.Spatial resolution of 1.1 mm was achieved with the coincidence imaging system using a 22Na point source.These results suggest that the gamma-ray imagers offer excellent potential for applications in high spatial medical imaging.