Abstract

The potential image quality and resolution of medical ultrasonic imaging catheters (UIC) for use in minimally invasive determinations of vascular disease was examined with the aid of a prototype, small-aperture, high-resolution imaging system. The value of high-resolution ultrasonic imaging derives from the potential ability to quantitate intimal roughening, 'see' beyond the intimal lining of the vessel, and compute tissue attenuation to help identify tissue histology. High-resolution images of an in vitro human arterial samples were obtained using the prototype UIC. Excellent correlations between the ultrasonic images, high-resolution, magnetic resonance images, and pathology specimens are demonstrated. It is concluded that high-quality images for small, clinically useful UICs are definitely feasible using current technology.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>

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