Abstract
In patients with CSF rhinorrhea, accurate identification of the CSF leakage site is crucial for surgical planning. We describe the application of a novel gadolinium-enhanced high-resolution 3D compressed-sensing T1 SPACE technique for MR cisternography and compare findings with CT cisternography and intraoperative results. In our pilot experience with 7 patients, precise detection of CSF leaks was feasible using compressed-sensing T1 SPACE, which appeared to be superior to CT cisternography.
Highlights
ABBREVIATIONS: CS 1⁄4 compressed-sensing; CTC 1⁄4 CT cisternography; MRC 1⁄4 MR cisternography; SPACE 1⁄4 sampling perfection with application-optimized contrasts by using different flip angle evolutio
116 Duman Jan 2021 www.ajnr.org blood imaging capabilities.[3]. The use of this technique for MRC after intrathecal gadolinium application may be advantageous because it offers a global 3D view of the entire skull base, meninges, and brain with high spatial detail and high SNR and contrast-to-noise ratio
After introduction of a novel CS T1 SPACE MRC technique, we perform combined CTC and MRC in all patients with CSF rhinorrhea confirmed by positive B2-transferrin test result
Summary
ABBREVIATIONS: CS 1⁄4 compressed-sensing; CTC 1⁄4 CT cisternography; MRC 1⁄4 MR cisternography; SPACE 1⁄4 sampling perfection with application-optimized contrasts by using different flip angle evolutio. High-resolution CT is commonly the initial noninvasive study of choice, it may not be sufficient to accurately determine the location of a CSF leak.[1,2] Intrathecal gadolinium-enhanced MR cisternography (MRC) has been recently introduced with studies reporting its safety and success in locating cranial CSF fistulas.1,2
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