Abstract

Background and Objectives: Due to inferior survival rates compared to hip and knee arthroplasty, total ankle arthroplasty (TAA) was previously mainly recommended for older and less active patients. However, given the encouraging survival rates and clinical outcomes of modern generations of TAA, some authors have also advocated TAA in young patients. Thus, the aim of this study was to evaluate age related reoperation, revision and survival rates of third-generation mobile-bearing TAAs. Materials and Methods: In this retrospective study, 224 consecutive TAA patients with a minimum follow up (FU) of 2 years were analyzed. Patients were retrospectively assigned to two study groups (Group A: age < 50 years; Group B: age ≥ 50 years). Revision was defined as secondary surgery with prothesis component removal, while reoperation was defined as a non-revisional secondary surgery involving the ankle. Results: After a mean FU of 7.1 ± 3.2 years, the reoperation rate (Group A: 22.2%; Group B: 5.3%; p = 0.003) and revision rate (Group A: 36.1%; Group B: 13.8%; p = 0.003) were higher within Group A. An age of under 50 years at time of surgery was associated with higher reoperation (odds ratio (OR): 6.54 (95% CI: 1.96–21.8); p = 0.002) and revision rates (OR: 3.13 (95% CI: 1.22–8.04); p = 0.018). Overall, lower patient age was associated with higher reoperation (p = 0.009) and revision rates (p = 0.001). Conclusions: The ideal indication for TAA remains controversial, especially regarding patient age. The findings of this study show high reoperation and revision rates in patients aged under 50 years at time of surgery. Therefore, the outcomes of this study suggest that the indication for TAA in young patients should be considered very carefully and that the association between low patient age and high reoperation rate should be disclosed to all eligible patients.

Highlights

  • While arthroplasty is the gold standard for the treatment of end-stage osteoarthritis (OA) in the hip and knee, arthrodesis has been the treatment of choice for the ankle in the past [1,2]

  • The intended advantages of total ankle arthroplasty (TAA) are good residual mobility and improved function compared to arthrodesis [11,12]

  • The ideal indication for TAA remains controversial, especially when it comes to the treatment of patients aged under 50 years

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Summary

Introduction

While arthroplasty is the gold standard for the treatment of end-stage osteoarthritis (OA) in the hip and knee, arthrodesis has been the treatment of choice for the ankle in the past [1,2]. Previous studies have reported encouraging survival rates for newer generations of total ankle arthroplasties (TAAs), so the arthroplasty of the ankle is gaining in popularity [3,4,5,6,7,8,9]. The intended advantages of TAA are good residual mobility and improved function compared to arthrodesis [11,12]. An improved mobility of the ankle joint is intended to reduce the risk of subsequent OA in adjacent joints [11,12,13,14,15,16]. Due to its inferior survival rates compared to hip and knee replacement, TAA was mainly recommended for older and less active patients in the past [17,18,19]

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