Abstract
Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time RT-PCR assay with norovirus type specific primers and probes. Of the 257 stool specimens tested, 28.4 % were norovirus positive. GII (71.2%) was the predominant strain followed by GI (20.5%), GI+GII (6.8%) and GIV (1.4%). Half of the norovirus positive stools (n=37) were co-infected with other pathogens. Continued surveillance of norovirus together with other viral and bacterial pathogens in hospitalized gastroenteritis patients as well as in the community will further elucidate the role and burden of different pathogens in diarrheal diseases.
Highlights
Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified
In this study the presence of NoV RNA in stool specimens from diarrheal patients admitted to three geographically distant hospitals in Bangladesh was investigated using real time PCR
The second most common enteric pathogen was rotavirus 70/257 (27.3%) and a substantial proportion 108/257 (42%) of diarrheal patients were negative for any pathogens tested in our study
Summary
Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. Methodology: Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time RT-PCR assay with norovirus type specific primers and probes. Recent reports from around the world indicate that NoV has become one of the most commonly identified pathogens and is responsible for the hospitalization for severe gastroenteritis of 12% of children less than 5 years of age (range 4.4-30.7%) [1,2,3,4]. In this study the presence of NoV RNA in stool specimens from diarrheal patients admitted to three geographically distant hospitals (one urban and two rural) in Bangladesh was investigated using real time PCR
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
