High Prevalence of Colon Polyps in Patients With Endometrial Polyps: A Study in a Minority Population

Abstract

Introduction: Previous studies have evaluated the association between colon and endometrial polyps in relation to Lynch syndrome. However, the association between these polyps is not well characterized among African Americans, a population at high risk for colorectal cancer.Table: Table. Demographic characteristicsMethods: We reviewed records of patients that had confirmed endometrial polyps and underwent colonoscopy (n=106) between 2004 and 2015. Colonoscopy reports for these 106 were reviewed for colon polyps' presence. Age-matched colonoscopy controls from 2004 to 2015 was used to determine colorectal polyps' prevalence independently of endometrial lesions.Colon polyps' occurrence was categorized by age groups. Software used for statistical analysis was STATA 14. Results: Among the 106 patients with endometrial polyps, 67 (63%) had colorectal polyps as well. In the female control population, the prevalence of colon polyps for the same time-period was 72 (43%). There were 24 tubular adenomas, 21 hyperplastic, 6 mixed and 16 undocumented polyps in the endometrial polyp group. Upon age groups categorization, 5% of colon polyps were in patients 31-40 years, 15% in patients 41-50 years, 40% in patients 51-60 years, 31% in patients 61-70 years and 9% in patients 71-80 years. Overall, 60% of the colon polyps in the endometrial polyps group occurred before age 60. Conclusion: Our study reveals a higher prevalence of colon neoplasia in females with endometrial polyps.It suggests that endometrial lesions may be associated with colonic neoplasia.Therefore, and as such further studies are needed to determine whether females with endometrial polyps would benefit from an increased colorectal neoplasia screening and surveillance.