Abstract
The effects of high perilymphatic K + and Rb + concentrations (20 mM) on the posterior canal resting discharge have been examined in the isolated frog labyrinth. Both K + and Rb + produced an increase in spike frequency which is sustained by a parallel increase in the excitatory postsynaptic potential (EPSP) emission rate. High K + and Rb + levels reduce the size of the afferent spike, broaden its time course but do not induce repetitive activity at the axon level. The K + and Rb + facilitation proved to be inversely related to the fibre's initial resting activity. The facilitation produced by increased K + was usually larger than that in Rb + solution. High sensitive and low sensitive units with similar low resting discharge were detected in relation to their response either to K + or Rb +. The effects of both ions can be explained on the basis of their interactions with the presynaptic hair cell currents.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
