Abstract
Methods developed for the separation of eburnane alkaloids have been applied for solving different analytical problems; plant extracts, mother liquors and pharmaceutical formulations have been analysed on both reversed-phase and silica packings. For the determination of apovincaminic acid ethyl ester (vinpocetine) in human blood plasma octylsilica was used as the stationary phase and acetonitrile–0.01 M aqueous ammonium carbonate as the eluent. For quantitation apovincamine can be used as an internal standard. The detection limit was found to be 2 ng/ml. To determine the corresponding acids of ester derivatives of eburnane alkaloids a reversed-phase ion-pair chromatographic method was developed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
