Abstract
SUMMARY High-performance liquid chromatography (hplc) was used to determine the phospholipid (pl) composition of ovine, equine, bovine, porcine, and canine RBC membranes. Procedural modifications of established techniques provided for separation of 7 pl within a 15- to 20-minute sample run. Significant (P < 0.05) differences were detected in rbc membrane pl composition among the various species. The concern for physiologic properties associated with hemolysis and/or sedimentation rate must include evaluation of differences in the pl bilayer structure.
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