Abstract

Objective To observe the distribution of the higher order aberrations in Chinese young adults with myopia and analyze the relationships between refractive error and the higher order aberrations.Methods Monochromatic aberrations of the whole eye were measured with a COAS Shack-Hartmann wavefront analyzer including 42 emmetropic eyes and 1 12 myopic eyes.The root mean square(RMS)values for the subjects measured with pupil diameters from 3mm to 6mm with a 1mm interval were determined.Results The root mean square (RMS) values of spherical aberration(SA),coma,trefoil,total higher order aberration (tHOA) and 3rd-6th order aberrations were significantly different between emmetropic and myopic eyes with 3mm-6mm aperture.In circumstances of 5mm and 6mm aperture,the RMS of SA,trefoil,tHOA and 3rd,4th,6th order aberrations across emmetropic and refractive error groups were statistically significant.Pupil diameter affected higher order aberrations remarkably.The values of RMS were increased correspondingly with pupil dilated from 3mm to 6mm in all types of aberrations,in particular 3rd and 4th order aberrations.The large amount of individual difference was found both in the pattern and magnitude of high-order aberrations in each refractive group,high variability of distribution of SA and trefoil was statistically significant with 5mm and 6mm aperture respectively (F=2.74,P=0.0454;F=3.93.P=0.0102).Conclusions The higher order aberrations vary systematically with degree of ametropia.SA and trefoil is more discrete in myopia. Key words: Wavefront aberrations; Myopia; Pupil; Refraction; Ocular; Hartmann-Shack sensor

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