Abstract
In the progeny from crosses of bacteriophage T4B involving closely linked rII markers, there exist particles which upon growth are capable of producing r + recombinant progeny, but which themselves are neither genetically nor phenotypically r +. Evidence is presented that these particles are partial heterozygotes, which are structurally biparental (nonrecombinant heterozygotes) and which give as primary segregants the two parental types. A comparison of recombinant formation in bacteria infected with nonrecombinant heterozygotes and in bacteria infected with the two parental types is described. Cells infected with nonrecombinant heterozygotes produce a higher frequency of recombinant clones and larger clones of recombinants. These differences are ascribed to different mechanisms of recombinant formation in the two types of cells. It is suggested that nonrecombinant heterozygotes form recombinant segregants by some process inherent in their mode of reproduction. This property of the nonrecombinant heterozygote may account for the apparent positive correlation of neighboring exchanges characteristic of recombination over short segments of the phage genome.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
